Multiple news outlets are highlighting our study published in Neuron Cell Press, which uncovers a biological pathway that fuels glioblastoma growth. It shows that an existing HIV drug can disrupt this process in preclinical models—pointing to a promising new avenue for brain cancer therapy.

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We are proud to celebrate Dr Sheila Singh, who has been named one of Canada’s Most Powerful Women: Top 100 Award Winners for 2025 by the Women’s Executive Network (WXN). A testament to her visionary leadership in brain cancer research and impact across Canada’s STEM community.

Block Biosciences: McMaster startup aims to prevent cancer from spreading to the brain

Block Biosciences was co-founded by Jakob Magolan and Sheila Singh, both executive members of the university’s Global Nexus, after their breakthrough research was published in Cell Reports Medicine. The startup is working on a first-in-class precision medicine that will prevent secondary metastatic brain cancer. 

Many congratulations to Dr Singh! She has been appointed as the new Joint Head of the School of Cancer & Pharmaceutical Sciences and Head of the Comprehensive Cancer Centre. Her academic position at King’s will be as Professor of Neuro-oncology and Neurosurgery, and she will hold a senior strategic advisory role with Evelina London, part of Guy’s and St Thomas’ NHS Foundation Trust.

Singh Lab collaborated with the Cleveland Clinic and Case Comprehensive Cancer Center to find that a protein long associated with Alzheimer’s disease also helps lung cancer spread to the brain, a discovery that provides hope for potential treatment.Mark Foundation along with a panel of other brain cancer experts tackling this tough topic.

How can we accelerate the development of effective cell and gene therapies for GBM patients? Dr Singh at ACGT Mark Foundation along with a panel of other brain cancer experts tackling this tough topic.

A CTV News highlight on our groundbreaking Nature Medicine paper describing the development of ROBO1 CAR T cellsto target axonal guidance dependencies in glioblastoma.

The European Association for Cancer Research proudly hosted the inaugural Women in Leadership Workshop, featuring our very own Dr. Sheila Singh alongside 24 other distinguished women in principal investigator positions.

Congratulations to Dr. Sheila Singh on the renewal of her prestigious Tier 1 Canada Research Chair in Human Cancer Stem Cell Biology. This esteemed recognition highlights her outstanding contributions to the field and her continued dedication to advancing cancer research.

Undergraduate students Sabra Salim and Nikoo Aghaei (McMaster University) ranked third for their innovative proposal and presentation on “Novel Agents Targeting Diffuse Astrocytoma” for The Pam and Rolando Del Maestro Family Undergraduate Student Research Competition at 2018 Brain Tumour National Conference in Toronto, Ontario.

The Terry Fox New Frontiers Program Project Grant funded PhD student Maleeha Qazi’s novel study on targeting clonal heterogeneity in treatment-refractory glioblastoma with novel and empiric immunotherapies.

PhD student Chirayu Chokshi’s exciting work with CRISPR/Cas genome engineering was showcased at the 2018 Cold Spring Habor Laboratory Meeting.

PhD student David Bakhshinyan stepped into the boxing ring to raise funds and awareness for research on aggressive childhood brain cancer. He participated in the KO for KIDS Charity Event in Niagara Falls, which raised more than $100,000 for Pathstone foundation for teen mental health, BoxRun charitable foundation for Ronald McDonald House, and childhood cancer research at McMaster University.

Undergraduate student Ashley Adile made a video discussing clinical trials in a very un-clinical way, which was highlighted by Clinical Trials Ontario. Having started as a class project, the video has been well received by brain cancer patients, families, and the Brain Tumour Foundation of Canada.

Our dear friend and former Olympic Boxer, Mike Strange, continues to graciously raise funds and awareness for brain cancer research.

Dr. Sheila Singh named to The College of New Scholars, Artists and Scientists!